The Best American Vape Juice Brands Of 2025

Purity was founded in 2009 in Florida. This brand creates e-liquids with high PG concentrations, so they work best in MTL (Mouth To Lung) vape kits where they’ll produce discreet amounts of vapour for a cigarette-like inhale. Their flavours mostly feature unique tobacco and menthol blends, making them popular with vapers looking for familiar tastes.

Purity’s best selling flavour is Tribeca, a tobacco blend with a sweet twist. The robust and dark tobacco base is rounded out by notes of rich vanilla and smooth-tasting caramel. For something a bit more traditional, Turkish Tobacco is a straightforward tobacco blend with earthy and slightly spiced notes throughout. If you prefer a cooler vape, Sub Zero is a frosty blend of crisp mint and intense menthol.

Founded in 2011, in South California, Ruthless is one of our most popular USA e-liquid brands. Their best-selling blends focus heavily on fruit and soda flavours, but these expert mixologists have a number of dessert and tobacco blends under their belts too. No matter which one you go for, you can be sure you’re in for a quality vape.

Grape Drank is easily Ruthless’ most popular flavour, recreating the classic taste of sweet, rich and dark American-style grape soda. If you like a frosty blend, you can pick up Grape Drank On Ice, which adds an arctic exhale. Both Grape Drank On Ice and the original Grape Drank are available as nic salts too, so MTL vapers aren’t left behind. For a more tropical taste, Rise and Jungle Fever feature fusions of exotic fruit notes.

Pacha Mama was founded in 2014 in South California. The name comes from the Incan goddess Pachamama, who was believed to preside over crops, planting, and harvesting – which makes perfect sense when you learn that this brand focuses on authentic fruit and botanical flavours. They offer both high VG shortfills and nicotine salts, making them a good choice for DTL and MTL vapers alike.

Pacha Mama’s most popular vape juice is Strawberry Watermelon, which features a duo of sweet, fruity flavours. If you’d prefer something a little less sweet, Mint Leaf faithfully recreates the cool and slightly-floral taste of freshly-picked mint.

Since 2012, Californian brand Five Pawns has been crafting premium e-liquid based on their goal to balance the five tastes: sweet, bitter, sour, salty and umami. This focus on layered blends has provided us with staff and customer favourites such as Black Flag Risen, Grandmaster and Bowden’s Mate. Designed for vapers who appreciate layered blends, you’ll find notes like coffee, tobacco, dessert and fruit in their collection of complex vape juices.

The most popular Five Pawns e-liquid is Castle Long. This e-liquid features a smoky bourbon base followed by roasted almond, creamy coconut, sweet vanilla bean and brown sugar notes. Five Pawns vape juices are available in freebase and shortfill form with a 50% VG concentration, so they’re ideal for MTL vapers.

Monster Vape Labs was founded in Florida in 2014. They’ve created a number of ranges, such as Jam Monster, which focuses on sweet jam toast blends; Frozen Fruit Monster, which features fusions of fruit and ice; and Tobacco Monster, which features layered tobacco flavours. They offer shortfill and nicotine salt e-liquids so the range suits both DTL and MTL vapers.

The most popular Monster Vape e-liquid is Banana Ice, a simple blend of rich banana with a frosty ice exhale. If you’re after something more unique, Blackberry Jam features the flavour of fruity jam on toast – vaping toast might sound strange, but we think it adds a much needed savoury note to an otherwise very sweet flavour.

Glas was founded in 2014 in Los Angeles. These expert mixologists focus on blending authentic-tasting fruit and dessert notes to create carefully-layered flavours. They create high VG shortfill e-liquids, with some of their best-selling flavours coming in nic salt form too.

Glas’ most popular blend is Butterscotch Reserve, which combines a dark tobacco base with sweet caramel, soft vanilla and smooth-tasting butterscotch notes. If you’d prefer something a little lighter-tasting, Fresh Mango fuses the tropical flavour of mango with sweet pineapple and juicy blackcurrant notes for a balanced fruity vape.

For a brand that manages to capture the taste of some classic American desserts, candy, and even sugary cereal, take a look at Charlie’s Chalk Dust. They’ve been around since 2014, making popular high VG (including 60% VG) options that go great with sub ohm kits and DTL vaping. All of their e-liquids come as 50ml shortfills in 60ml bottles, so you can create your own 3mg e-liquid by adding a 18mg nic shot.

When it comes to recommendations, fans of rich dessert blends will find something to love with Campfire. This complex blend mimics the taste of smores with chocolate, graham cracker, marshmallow, and cinnamon notes fused together. But if it's the fruity options you’re searching for, try Mustache Milk, which tastes like fruity cereal, or Jam Rock for the flavour of green apple and candy.

If we were handing out awards for the wildest names, Suicide Bunny would be at the top of the charts. But, there’s more to the brand than just flashy artwork and outlandish labels. At its core, this range of shortfills is all about well-crafted, decadent flavours. They’ve truly stood the test of time and their recipes have never changed – because they didn’t need to.

They might not be cheap, but these blends stand out. Mother’s Milk is the perfect option if you’re searching for a sweet and creamy fusion, and it’s combination of strawberry and custard is often imitated but the original stands out. Fancy a break from desserts? Try Sucker Punch and its combination of exotic fruit, cream and menthol.

Naked 100 are based in California, and focus on creating e-liquids with unprocessed ingredients. Specialising in shortfills, Naked 100 makes a range of 70% VG vape juices that pair perfectly with sub ohm kits and make a large amount of vapour – ideal for DTL vaping. You can pick these blends up as 50ml of 0mg e-liquid, with enough space in the bottle to add a 10ml nic shot.

Whether you’re a fan of fruity flavours, or looking for a sweet tobacco blend, you’ll find it in the Naked 100 selection. Try American Patriots for a rich combination of tobacco and caramel notes, or give Lava Flow a go and experience a medley of strawberry, pineapple, and cream flavours. After some classic fruit options? Check out Very Cool and Hawaiian POG!

Rounding this list off is another pick straight from sunny California! Cosmic Fog are known for their range of 100ml shortfills, each boasting a 70% VG concentration making them ideal for DTL vapers. These 0mg shortfills come in a 120ml bottle, leaving you enough space to mix in up to two 18mg nic shots to make a 3mg vape juice.

Cosmic Fog specialises in unique blends you won’t find anywhere else, like Chill’d Tobacco that combines tobacco, chocolate, and peppermint flavours into one bold e-liquid. Or, check out Milk & Honey for a sweet blend of milk, honey, and marshmallow notes. Looking for something fruity? Well, Cosmic Fog delivers there too, with The Shocker providing a zingy fruit medley in every puff.